Fluoroform conversion

Conversion of fluoroform into fluorinated and non-PFAS reaction intermediates
Technology No.
1

Conversion of fluoroform into fluorinated and non-PFAS reaction intermediates

Fluoroform conversion

Background
The increasing demand for fluorinated compounds, particularly within the pharmaceutical and agrochemical sectors, necessitates the development of sustainable and efficient synthetic methodologies. Traditional production processes often generate significant environmental challenges, notably through the emission of potent greenhouse gases such as fluoroform (trifluoromethane), a by-product of polytetrafluoroethylene (PTFE or Teflon®) manufacturing. Conventionally, this gas is either incinerated or released into the atmosphere, contributing substantially to global warming.

Technology overview

A novel synthetic pathway has been established, enabling the efficient conversion of fluoroform into polyfluorinated molecules. These molecules serve as versatile intermediates for the synthesis of a broad spectrum of fluorinated compounds. The process utilises fluoroform, transforming an environmentally harmful waste product into valuable chemical building blocks.

Stage of Development

The technology has been successfully validated at laboratory scale, demonstrating feasibility. Ongoing efforts are directed towards process optimisation and pilot-scale production, with the aim of facilitating industrial adoption.

Benefits

  • Environment impact: Significantly reduces greenhouse gas emissions by repurposing fluoroform, a high global warming potential substance.
  • Sustainability: Promotes the valorisation of industrial by-products, fostering a circular economy approach.
  • Regulatory compliance: The resulting intermediates are not classified as PFAS under the 2024 European regulatory framework, ensuring adherence to current environmental standards.
  • Versatility: Provides access to a wide array of fluorinated compounds for advanced applications.

Applications
  • Pharmaceutical industry: Synthesis of active pharmaceutical ingredients and intermediates.
  • Agrochemical sector: Production of advanced crop protection agents and related compounds.
  • Specialty chemicals: Manufacture of high-performance materials and functional additives.

Opportunity

This innovation presents a compelling opportunity for industrial partners seeking to enhance sustainability, reduce environmental impact, and access high-value fluorinated intermediates. 

Seeking

Development partners, Licensing

IP

Patent application submitted (priority year 2024)
  • expand_more cloud_download Supporting documents (1)
    Fluoro (english version)
    OnePager_Fluoro_english.pdf (817 KB)
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